SPHINGOSINE-1-PHOSPHATE CAN BE FUN FOR ANYONE

The crystal structure of S1P1 has advised a potential system for ligand usage of the GPCR that entails insertion of S1P to the outer leaflet on the plasma membrane accompanied by lateral diffusion to enter the binding pocket (39). This implies that phosphatases close to the S1P receptors could regulate ligand access.The Potter PS10 Collection Strai